In the 1950s the pharmaceutical industry got the majority. Pharmaceutical German, Belgian, British, French, Swedish and Swiss developed new and effective drugs (and sometimes not so effective). The market was flooded with new antibiotics (penicillins chemically modified to destroy the bacteria have become resistant to older products), antihistamines to treat allergies such as hives or hay fever, new analgesics, sedatives and anesthetics, As pharmaceutical companies increasingly investing in research and development. The European newspaper headlines began to voice criticism about the lack of control of the sector following the thalidomide disaster. This drug was developed in Germany in 1953 and marketed in this country in 1956.The thalidomide was an effective treatment for depression in early pregnancy, a condition which often took some women to suicide. But in the late 1950s, it was observed that the number of babies born with incompletely developed members was statistically significantly higher among children of mothers treated with this drug. Further experiments with animals have shown that thalidomide damages the growth of members in the embryo and interrupted their normal development. The spread of this discovery was that the drug was withdrawn in all countries. The German company was accused of concealing evidence and disappeared so dishonorable. Since 1970 they settled in many countries government agencies for quality control, clinical testing and packaging, labeling and distribution of drugs.Granting authorizations for both drugs and their manufacturers and their inspectors have the right to visit any time the facilities for pharmaceutical products manufactured and stored. Other agencies are responsible for controlling the manufacture and distribution of medicines and animal growth. The distribution of numerous drugs available to the thousands of existing clinics and pharmacies would be almost impossible without the services of wholesale distributors strategically positioned to perform daily supplies. Local pharmacies, the last link in the chain of drug delivery to citizens, are inspected by officials responsible for the different ministries or departments of Health.