No doubt it looks like clinical depression. In addition, many of us have had the misfortune to suffer from depression. The abiding sadness, stress, decreased energy, inability to enjoy normal pleasures and autonomic disorders (nutrition, sleep and self-regulation) are obvious. (Similarly see: Futurist). Freud was the first to compare and contrast the depression ("melancholy") state the normal experience of grief. He discovered an important difference between these two conditions: with normal grief reactions experienced by the outside world how to reduce any significant way (loss of significant person), while in a depressed state, that is experienced as lost or destroyed, a part of himself. Consequently, in some sense the opposite of depression is the experience of grief. People who go through the process of grief in the normal way, not become depressed, even under the condition that they are deeply grieved over a period of time after a bereavement or loss. Psychologist, therapist will note that the cognitive, emotional, sensory processes and imagination is often drastically slowed down in a sudden clinical depression.

To serious violations of the end of the spectrum are patients who cruelly hate themselves and experiencing hallucinations, which are to discovery of antidepressants could absorb over the years devoted their efforts and therapists still uncritically believe that the best way to save the world is to destroy itself. Freud consistently developed the idea, that a major source of depression is the tendency to experience premature loss. In accordance with the classical theory of psychoanalysis, which assumes that people are fixed on the infantile stage, during which they were spoiled or subjected to deprivation, depression, individuals seen as people who have experienced a sudden or too early weaning or other early frustration, which exceeded their ability to adapt.